Sylvia Thelen, PhD
Signal Transduction
Scientist
Via Vela, 6
6500 Bellinzona,
Switzerland
- sylvia.thelen@irb.usi.ch
- +41 91 820 0337
- +41 91 820 0305
| Projects |
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| The guanine nucleotide exchange factor for Rac P-Rex1 |
| Publications |
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The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1alpha M. A. Barber, A. Hendrickx, M. Beullens, H. Ceulemans, D. Oxley, S. Thelen, M. Thelen, M. Bollen, H. C. Welch in Biochem J (2012) vol. 443 pp173-83 |
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Cxcl12 evolution - subfunctionalization of a ligand through altered interaction with the chemokine receptor B. Boldajipour, M. Doitsidou, K. Tarbashevich, C. Laguri, S. R. Yu, J. Ries, K. Dumstrei, S. Thelen, J. Dorries, E. M. Messerschmidt, M. Thelen, P. Schwille, M. Brand, H. Lortat-Jacob, E. Raz in Development (2011) vol. 138 pp2909-14 |
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Polarization of migrating monocytic cells is independent of PI 3-kinase activity S. Volpe, S. Thelen, T. Pertel, M. J. Lohse, M. Thelen in PLoS One (2010) vol. 5 ppe10159 |
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CXCR7, CXCR4 and CXCL12: an eccentric trio? M. Thelen, S. Thelen in J Neuroimmunol (2008) vol. 198 pp9-13 |
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Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase M. A. Barber, S. Donald, S. Thelen, K. E. Anderson, M. Thelen, H. C. Welch in J Biol Chem (2007) vol. 282 pp29967-76 |
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Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway P. Ogilvie, S. Thelen, B. Moepps, P. Gierschik, A. C. da Silva Campos, M. Baggiolini, M. Thelen in J Immunol (2004) vol. 172 pp6715-22 |
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Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation W. W. Agace, A. Amara, A. I. Roberts, J. L. Pablos, S. Thelen, M. Uguccioni, X. Y. Li, J. Marsal, F. Arenzana-Seisdedos, T. Delaunay, E. C. Ebert, B. Moser, C. M. Parker in Curr Biol (2000) vol. 10 pp325-8 |