Publications

2012

Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses
A. Viejo-Borbolla, N. Martinez-Martin, H. J. Nel, P. Rueda, R. Martin, S. Blanco, F. Arenzana-Seisdedos, M. Thelen, P. G. Fallon, A. Alcami
in PLoS Pathog (2012) vol. 8 ppe1002497

The Guanine-Nucleotide Exchange Factor (GEF) PRex1 is Activated by Protein Phosphatase 1alpha (PP1alpha)
M. A. Barber, A. Hendrickx, M. Beullens, H. Ceulemans, D. Oxley, S. Thelen, M. Thelen, M. Bollen, H. C. Welch
in Biochem J (2012)

2011

Ralph M. Steinman 1943-2011
A. Lanzavecchia, F. Sallusto
in Cell (2011) vol. 147 pp1216-7

MiR-146a in Immunity and Disease
N. Rusca, S. Monticelli
in Mol Biol Int (2011) vol. 2011 pp437301

MiR-221 Influences Effector Functions and Actin Cytoskeleton in Mast Cells
R. J. Mayoral, L. Deho, N. Rusca, N. Bartonicek, H. K. Saini, A. J. Enright, S. Monticelli
in PLoS One (2011) vol. 6 ppe26133

Characterization of Neutralizing Profiles in HIV-1 Infected Patients from whom the HJ16, HGN194 and HK20 mAbs were Obtained
S. S. Balla-Jhagjhoorsingh, B. Willems, L. Heyndrickx, K. Vereecken, W. Janssens, M. S. Seaman, D. Corti, A. Lanzavecchia, D. Davis, G. Vanham
in PLoS One (2011) vol. 6 ppe25488

Unconventional Use of LC3 by Coronaviruses through the Alleged Subversion of the ERAD Tuning Pathway
F. Reggiori, C. A. de Haan, M. Molinari
in Viruses (2011) vol. 3 pp1610-23

Memory in disguise
F. Sallusto, A. Lanzavecchia
in Nat Med (2011) vol. 17 pp1182-3

Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes
M. A. Schmid, H. Takizawa, D. R. Baumjohann, Y. Saito, M. G. Manz
in Blood (2011) vol. 118 pp4829-40

HTLV-1 Propels Thymic Human T Cell Development in "Human Immune System" Rag2 gamma c Mice
J. Villaudy, M. Wencker, N. Gadot, N. A. Gillet, J. Y. Scoazec, L. Gazzolo, M. G. Manz, C. R. Bangham, M. D. Dodon
in PLoS Pathog (2011) vol. 7 ppe1002231

IL-36R ligands are potent regulators of dendritic and T cells
S. Vigne, G. Palmer, C. Lamacchia, P. Martin, D. Talabot-Ayer, E. Rodriguez, F. Ronchi, F. Sallusto, H. Dinh, J. E. Sims, C. Gabay
in Blood (2011) vol. 118 pp5813-23

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
M. T. Pallotta, C. Orabona, C. Volpi, C. Vacca, M. L. Belladonna, R. Bianchi, G. Servillo, C. Brunacci, M. Calvitti, S. Bicciato, E. M. Mazza, L. Boon, F. Grassi, M. C. Fioretti, F. Fallarino, P. Puccetti, U. Grohmann
in Nat Immunol (2011) vol. 12 pp870-8

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
D. Corti, J. Voss, S. J. Gamblin, G. Codoni, A. Macagno, D. Jarrossay, S. G. Vachieri, D. Pinna, A. Minola, F. Vanzetta, C. Silacci, B. M. Fernandez-Rodriguez, G. Agatic, S. Bianchi, I. Giacchetto-Sasselli, L. Calder, F. Sallusto, P. Collins, L. F. Haire, N. Temperton, J. P. Langedijk, J. J. Skehel, A. Lanzavecchia
in Science (2011) vol. 333 pp850-6

Efficient differentiation and function of human macrophages in humanized CSF-1 mice
C. Rathinam, W. T. Poueymirou, J. Rojas, A. J. Murphy, D. M. Valenzuela, G. D. Yancopoulos, A. Rongvaux, E. E. Eynon, M. G. Manz, R. A. Flavell
in Blood (2011) vol. 118 pp3119-28

Pharmacologic P2X purinergic receptor antagonism in the treatment of collagen-induced arthritis
V. Ardissone, E. Radaelli, P. Zaratin, M. Ardizzone, C. Ladel, M. Gattorno, A. Martini, F. Grassi, E. Traggiai
in Arthritis Rheum (2011) vol. 63 pp3323-32

Transgenic expression of human signal regulatory protein alpha in Rag2-/-{gamma}c-/- mice improves engraftment of human hematopoietic cells in humanized mice
T. Strowig, A. Rongvaux, C. Rathinam, H. Takizawa, C. Borsotti, W. Philbrick, E. E. Eynon, M. G. Manz, R. A. Flavell
in Proc Natl Acad Sci U S A (2011) vol. 108 pp13218-23

T regulatory cells are markers of disease activity in multiple sclerosis patients
D. Dalla Libera, D. Di Mitri, A. Bergami, D. Centonze, C. Gasperini, M. G. Grasso, S. Galgani, V. Martinelli, G. Comi, C. Avolio, G. Martino, G. Borsellino, F. Sallusto, L. Battistini, R. Furlan
in PLoS One (2011) vol. 6 ppe21386

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection
R. de Alwis, M. Beltramello, W. B. Messer, S. Sukupolvi-Petty, W. M. Wahala, A. Kraus, N. P. Olivarez, Q. Pham, J. Brian, W. Y. Tsai, W. K. Wang, S. Halstead, S. Kliks, M. S. Diamond, R. Baric, A. Lanzavecchia, F. Sallusto, A. M. de Silva
in PLoS Negl Trop Dis (2011) vol. 5 ppe1188

Cxcl12 evolution - subfunctionalization of a ligand through altered interaction with the chemokine receptor
B. Boldajipour, M. Doitsidou, K. Tarbashevich, C. Laguri, S. R. Yu, J. Ries, K. Dumstrei, S. Thelen, J. Dorries, E. M. Messerschmidt, M. Thelen, P. Schwille, M. Brand, H. Lortat-Jacob, E. Raz
in Development (2011) vol. 138 pp2909-14

High throughput cellular screens to interrogate the human T and B cell repertoires
D. Corti, F. Sallusto, A. Lanzavecchia
in Curr Opin Immunol (2011) vol. 23 pp430-5

Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool
O. Marroquin Belaunzaran, M. I. Cordero, V. Setola, S. Bianchi, C. Galli, N. Bouche, V. Mlynarik, R. Gruetter, C. Sandi, J. C. Bensadoun, M. Molinari, P. Aebischer
in PLoS One (2011) vol. 6 ppe18268

An Anti-HIV-1 V3 Loop Antibody Fully Protects Cross-Clade and Elicits T-Cell Immunity in Macaques Mucosally Challenged with an R5 Clade C SHIV
J. D. Watkins, N. B. Siddappa, S. K. Lakhashe, M. Humbert, A. Sholukh, G. Hemashettar, Y. L. Wong, J. K. Yoon, W. Wang, F. J. Novembre, F. Villinger, C. Ibegbu, K. Patel, D. Corti, G. Agatic, F. Vanzetta, S. Bianchi, J. L. Heeney, F. Sallusto, A. Lanzavecchia, R. M. Ruprecht
in PLoS One (2011) vol. 6 ppe18207

CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses
N. Chevalier, D. Jarrossay, E. Ho, D. T. Avery, C. S. Ma, D. Yu, F. Sallusto, S. G. Tangye, C. R. Mackay
in J Immunol (2011) vol. 186 pp5556-68

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors
U. Schenk, M. Frascoli, M. Proietti, R. Geffers, E. Traggiai, J. Buer, C. Ricordi, A. M. Westendorf, F. Grassi
in Sci Signal (2011) vol. 4 ppra12

Dissecting the human immunologic memory for pathogens
C. E. Zielinski, D. Corti, F. Mele, D. Pinto, A. Lanzavecchia, F. Sallusto
in Immunol Rev (2011) vol. 240 pp40-51

Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors
E. D. Quakkelaar, A. Redeker, E. K. Haddad, A. Harari, S. M. McCaughey, T. Duhen, A. Filali-Mouhim, J. P. Goulet, N. M. Loof, F. Ossendorp, B. Perdiguero, P. Heinen, C. E. Gomez, K. V. Kibler, D. M. Koelle, R. P. Sekaly, F. Sallusto, A. Lanzavecchia, G. Pantaleo, M. Esteban, J. Tartaglia, B. L. Jacobs, C. J. Melief
in PLoS One (2011) vol. 6 ppe16819

Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin
M. Pedotti, L. Simonelli, E. Livoti, L. Varani
in Int J Mol Sci (2011) vol. 12 pp226-51

Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
H. Takizawa, R. R. Regoes, C. S. Boddupalli, S. Bonhoeffer, M. G. Manz
in J Exp Med (2011) vol. 208 pp273-84

Malectin Participates in a Backup Glycoprotein Quality Control Pathway in the Mammalian ER
C. Galli, R. Bernasconi, T. Solda, V. Calanca, M. Molinari
in PLoS One (2011) vol. 6 ppe16304

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung
T. Willinger, A. Rongvaux, H. Takizawa, G. D. Yancopoulos, D. M. Valenzuela, A. J. Murphy, W. Auerbach, E. E. Eynon, S. Stevens, M. G. Manz, R. A. Flavell
in Proc Natl Acad Sci U S A (2011) vol. 108 pp2390-5

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo
A. Rongvaux, T. Willinger, H. Takizawa, C. Rathinam, W. Auerbach, A. J. Murphy, D. M. Valenzuela, G. D. Yancopoulos, E. E. Eynon, S. Stevens, M. G. Manz, R. A. Flavell
in Proc Natl Acad Sci U S A (2011) vol. 108 pp2378-83

Strain-Transcending Fc-Dependent Killing of Plasmodium falciparum by Merozoite Surface Protein 2 Allele-Specific Human Antibodies
J. Stubbs, S. Olugbile, B. Saidou, J. Simpore, G. Corradin, A. Lanzavecchia
in Infect Immun (2011) vol. 79 pp1143-52

Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes
Z. Kou, J. Y. Lim, M. Beltramello, M. Quinn, H. Chen, S. N. Liu, L. Martnez-Sobrido, M. S. Diamond, J. J. Schlesinger, A. de Silva, F. Sallusto, X. Jin
in Virology (2011) vol. 410 pp240-7

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER
R. Bernasconi, M. Molinari
in Curr Opin Cell Biol (2011) vol. 23 pp176-183

Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP
A. Casati, M. Frascoli, E. Traggiai, M. Proietti, U. Schenk, F. Grassi
in Cell Death Differ (2011) vol. 18 pp396-404

2010

Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41
C. Sabin, D. Corti, V. Buzon, M. S. Seaman, D. Lutje Hulsik, A. Hinz, F. Vanzetta, G. Agatic, C. Silacci, L. Mainetti, G. Scarlatti, F. Sallusto, R. Weiss, A. Lanzavecchia, W. Weissenhorn
in PLoS Pathog (2010) vol. 6 ppe1001195

CD4(+) CD25(+) Treg regulate the contribution of CD8(+) T-cell subsets in repopulation of the lymphopenic environment
A. R. Almeida, I. F. Ciernik, F. Sallusto, A. Lanzavecchia
in Eur J Immunol (2010) vol. 40 pp3478-88

Chondroitin Sulfate A-Adhering Plasmodium falciparum-Infected Erythrocytes Express Functionally Important Antibody Epitopes Shared by Multiple Variants
L. Barfod, T. Dobrilovic, P. Magistrado, P. Khunrae, F. Viwami, J. Bruun, M. Dahlback, N. L. Bernasconi, M. Fried, D. John, P. E. Duffy, A. Salanti, A. Lanzavecchia, C. T. Lim, N. T. Ndam, M. K. Higgins, L. Hviid
in J Immunol (2010) vol. 185 pp7553-61

From vaccines to memory and back
F. Sallusto, A. Lanzavecchia, K. Araki, R. Ahmed
in Immunity (2010) vol. 33 pp451-63

Monocytes join the dendritic cell family
F. Sallusto, A. Lanzavecchia
in Cell (2010) vol. 143 pp339-40

Cyclosporine a-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation
R. Bernasconi, T. Solda, C. Galli, T. Pertel, J. Luban, M. Molinari
in PLoS One (2010) vol. 5 ppe13008

Perivascular expression of CXCL9 and CXCL12 in primary central nervous system lymphoma: T-cell infiltration and positioning of malignant B cells
D. Venetz, M. Ponzoni, M. Schiraldi, A. J. Ferreri, F. Bertoni, C. Doglioni, M. Uguccioni
in Int J Cancer (2010) vol. 127 pp2300-12

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity
M. Beltramello, K. L. Williams, C. P. Simmons, A. Macagno, L. Simonelli, N. T. Quyen, S. Sukupolvi-Petty, E. Navarro-Sanchez, P. R. Young, A. M. de Silva, F. A. Rey, L. Varani, S. S. Whitehead, M. S. Diamond, E. Harris, A. Lanzavecchia, F. Sallusto
in Cell Host Microbe (2010) vol. 8 pp271-83

Stable Overexpression of miRNAs in Bone Marrow-Derived Murine Mast Cells Using Lentiviral Expression Vectors
R. J. Mayoral, S. Monticelli
in Methods Mol Biol (2010) vol. 667 pp205-14

Autophagy-independent LC3 function in vesicular traffic
C. A. de Haan, M. Molinari, F. Reggiori
in Autophagy (2010) vol. 6 pp994-6

T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays
S. F. Martin, P. R. Esser, S. Schmucker, L. Dietz, D. J. Naisbitt, B. K. Park, M. Vocanson, J. F. Nicolas, M. Keller, W. J. Pichler, M. Peiser, A. Luch, R. Wanner, E. Maggi, A. Cavani, T. Rustemeyer, A. Richter, H. J. Thierse, F. Sallusto
in Cell Mol Life Sci (2010) vol. 67 pp4171-84

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness
J. Pietzsch, J. F. Scheid, H. Mouquet, F. Klein, M. S. Seaman, M. Jankovic, D. Corti, A. Lanzavecchia, M. C. Nussenzweig
in J Exp Med (2010) vol. 207 pp1995-2002

Purinergic control of neutrophil activation
F. Grassi
in J Mol Cell Biol (2010) vol. 2 pp176-7

Selective preservation of bone marrow mature recirculating but not marginal zone B cells in murine models of chronic inflammation
E. Traggiai, A. Casati, M. Frascoli, S. Porcellini, M. Ponzoni, F. Sanvito, L. Leng, R. Bucala, L. Moretta, F. Grassi
in PLoS One (2010) vol. 5 ppe11262

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome
B. Cassani, P. L. Poliani, V. Marrella, F. Schena, A. V. Sauer, M. Ravanini, D. Strina, C. E. Busse, S. Regenass, H. Wardemann, A. Martini, F. Facchetti, M. van der Burg, A. G. Rolink, P. Vezzoni, F. Grassi, E. Traggiai, A. Villa
in J Exp Med (2010) vol. 207 pp1525-40

Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication
F. Reggiori, I. Monastyrska, M. H. Verheije, T. Cali, M. Ulasli, S. Bianchi, R. Bernasconi, C. A. de Haan, M. Molinari
in Cell Host Microbe (2010) vol. 7 pp500-8

Current Opinion in Immunology. Vaccines. Introduction
H. C. Ertl, A. Lanzavecchia
in Curr Opin Immunol (2010) vol. 22 pp355-7

Human mast cells and mastocytosis: harnessing microRNA expression as a new approach to therapy?
L. Deho, S. Monticelli
in Arch Immunol Ther Exp (Warsz) (2010) vol. 58 pp279-86

Polarization of migrating monocytic cells is independent of PI 3-kinase activity
S. Volpe, S. Thelen, T. Pertel, M. J. Lohse, M. Thelen
in PLoS One (2010) vol. 5 ppe10159

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
D. Corti, A. L. Suguitan, D. Pinna, C. Silacci, B. M. Fernandez-Rodriguez, F. Vanzetta, C. Santos, C. J. Luke, F. J. Torres-Velez, N. J. Temperton, R. A. Weiss, F. Sallusto, K. Subbarao, A. Lanzavecchia
in J Clin Invest (2010) vol. 120 pp1663-73

CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function
L. Rivino, P. Gruarin, B. Haringer, S. Steinfelder, L. Lozza, B. Steckel, A. Weick, E. Sugliano, D. Jarrossay, A. A. Kuhl, C. Loddenkemper, S. Abrignani, F. Sallusto, A. Lanzavecchia, J. Geginat
in J Exp Med (2010) vol. 207 pp565-77

Instructive cytokine signals in dendritic cell lineage commitment
M. A. Schmid, D. Kingston, S. Boddupalli, M. G. Manz
in Immunol Rev (2010) vol. 234 pp32-44

CXCR7 functions as a scavenger for CXCL12 and CXCL11
U. Naumann, E. Cameroni, M. Pruenster, H. Mahabaleshwar, E. Raz, H. G. Zerwes, A. Rot, M. Thelen
in PLoS One (2010) vol. 5 ppe9175

Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus
B. Rockx, E. Donaldson, M. Frieman, T. Sheahan, D. Corti, A. Lanzavecchia, R. S. Baric
in J Infect Dis (2010) vol. 201 pp946-55

Development of monocytes, macrophages, and dendritic cells
F. Geissmann, M. G. Manz, S. Jung, M. H. Sieweke, M. Merad, K. Ley
in Science (2010) vol. 327 pp656-61

Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates
R. Bernasconi, C. Galli, V. Calanca, T. Nakajima, M. Molinari
in J Cell Biol (2010) vol. 188 pp223-35

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
D. Corti, J. P. Langedijk, A. Hinz, M. S. Seaman, F. Vanzetta, B. M. Fernandez-Rodriguez, C. Silacci, D. Pinna, D. Jarrossay, S. Balla-Jhagjhoorsingh, B. Willems, M. J. Zekveld, H. Dreja, E. O'Sullivan, C. Pade, C. Orkin, S. A. Jeffs, D. C. Montefiori, D. Davis, W. Weissenhorn, A. McKnight, J. L. Heeney, F. Sallusto, Q. J. Sattentau, R. A. Weiss, A. Lanzavecchia
in PLoS One (2010) vol. 5 ppe8805

Rapid structural characterization of human antibody-antigen complexes through experimentally validated computational docking
L. Simonelli, M. Beltramello, Z. Yudina, A. Macagno, L. Calzolai, L. Varani
in J Mol Biol (2010) vol. 396 pp1491-507

ERAD substrates: which way out?
D. N. Hebert, R. Bernasconi, M. Molinari
in Semin Cell Dev Biol (2010) vol. 21 pp526-32

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
L. Dolcetti, E. Peranzoni, S. Ugel, I. Marigo, A. Fernandez Gomez, C. Mesa, M. Geilich, G. Winkels, E. Traggiai, A. Casati, F. Grassi, V. Bronte
in Eur J Immunol (2010) vol. 40 pp22-35

Isolation of common dendritic cell progenitors (CDP) from mouse bone marrow
N. Onai, M. G. Manz, M. A. Schmid
in Methods Mol Biol (2010) vol. 595 pp195-203

Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex
A. Macagno, N. L. Bernasconi, F. Vanzetta, E. Dander, A. Sarasini, M. G. Revello, G. Gerna, F. Sallusto, A. Lanzavecchia
in J Virol (2010) vol. 84 pp1005-13

N-glycan structures: recognition and processing in the ER
M. Aebi, R. Bernasconi, S. Clerc, M. Molinari
in Trends Biochem Sci (2010) vol. 35 pp74-82

Chemokine receptor oligomerization: functional considerations
M. Thelen, L. M. Munoz, J. M. Rodriguez-Frade, M. Mellado
in Curr Opin Pharmacol (2010) vol. 10 pp38-43

MicroRNAs and the Immune System
S. Monticelli
in Methods in Molecular Biology (2010) vol. 667 pp330p.

2009

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
M. R. Neagu, P. Ziegler, T. Pertel, C. Strambio-De-Castillia, C. Grutter, G. Martinetti, L. Mazzucchelli, M. Grutter, M. G. Manz, J. Luban
in J Clin Invest (2009) vol. 119 pp3035-47

Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity
F. Sallusto, A. Lanzavecchia
in Eur J Immunol (2009) vol. 39 pp2076-82

Humanized mice for modeling human infectious disease: challenges, progress, and outlook
N. Legrand, A. Ploss, R. Balling, P. D. Becker, C. Borsotti, N. Brezillon, J. Debarry, Y. de Jong, H. Deng, J. P. Di Santo, S. Eisenbarth, E. Eynon, R. A. Flavell, C. A. Guzman, N. D. Huntington, D. Kremsdorf, M. P. Manns, M. G. Manz, J. J. Mention, M. Ott, C. Rathinam, C. M. Rice, A. Rongvaux, S. Stevens, H. Spits, H. Strick-Marchand, H. Takizawa, A. U. van Lent, C. Wang, K. Weijer, T. Willinger, P. Ziegler
in Cell Host Microbe (2009) vol. 6 pp5-9

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
T. Duhen, R. Geiger, D. Jarrossay, A. Lanzavecchia, F. Sallusto
in Nat Immunol (2009) vol. 10 pp857-63

Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells
R. Geiger, T. Duhen, A. Lanzavecchia, F. Sallusto
in J Exp Med (2009) vol. 206 pp1525-34

Flt3L, DCs, and NTregs: team contra GVHD?
M. G. Manz
in Blood (2009) vol. 113 pp6267-8

Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein
D. Voss, S. Pfefferle, C. Drosten, L. Stevermann, E. Traggiai, A. Lanzavecchia, S. Becker
in Virol J (2009) vol. 6 pp79

Human B cell memory
A. Lanzavecchia, F. Sallusto
in Curr Opin Immunol (2009) vol. 21 pp298-304

Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
J. Soerli, L. Barfod, T. Lavstsen, N. L. Bernasconi, A. Lanzavecchia, L. Hviid
in Parasite Immunol (2009) vol. 31 pp341-6

The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis
D. Kingston, M. A. Schmid, N. Onai, A. Obata-Onai, D. Baumjohann, M. G. Manz
in Blood (2009) vol. 114 pp835-43

The Diversity of Nuclear Magnetic Resonance Spectroscopy
C. W. Liu, V. Y. Alekseyev, J. R. Allwardt, A. J. Bankovich, B. J. Cade-Menun, R. W. Davis, L. S. Du, K. C. Garcia, D. Herschlag, C. Khosla, D. A. Kraut, Q. Li, B. Null, J. D. Puglisi, P. A. Sigala, J. F. Stebbins, L. Varani
in Biophysics and the Challenges of Emerging Threats (2009) pp65-81

Clonal dissection of the human memory B-cell repertoire following infection and vaccination
D. Pinna, D. Corti, D. Jarrossay, F. Sallusto, A. Lanzavecchia
in Eur J Immunol (2009) vol. 39 pp1260-70

Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells
G. Napolitani, E. V. Acosta-Rodriguez, A. Lanzavecchia, F. Sallusto
in Eur J Immunol (2009) vol. 39 pp1301-12

Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets
S. Khurana, A. L. Suguitan, Y. Rivera, C. P. Simmons, A. Lanzavecchia, F. Sallusto, J. Manischewitz, L. R. King, K. Subbarao, H. Golding
in PLoS Med (2009) vol. 6 ppe1000049

Human Th17 cells in infection and autoimmunity
F. Sallusto, A. Lanzavecchia
in Microbes Infect (2009) vol. 11 pp620-4

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques
C. Stahl-Hennig, M. Eisenblatter, E. Jasny, T. Rzehak, K. Tenner-Racz, C. Trumpfheller, A. M. Salazar, K. Uberla, K. Nieto, J. Kleinschmidt, R. Schulte, L. Gissmann, M. Muller, A. Sacher, P. Racz, R. M. Steinman, M. Uguccioni, R. Ignatius
in PLoS Pathog (2009) vol. 5 ppe1000373

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
A. Reboldi, C. Coisne, D. Baumjohann, F. Benvenuto, D. Bottinelli, S. Lira, A. Uccelli, A. Lanzavecchia, B. Engelhardt, F. Sallusto
in Nat Immunol (2009) vol. 10 pp514-23

Synergy-inducing chemokines enhance CCR2 ligand activities on monocytes
K. Kuscher, G. Danelon, S. Paoletti, L. Stefano, M. Schiraldi, V. Petkovic, M. Locati, B. O. Gerber, M. Uguccioni
in Eur J Immunol (2009) vol. 39 pp1118-28

Dendritic cell homeostasis
M. Merad, M. G. Manz
in Blood (2009) vol. 113 pp3418-27

An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding
S. Sebastian, C. Grutter, C. Strambio de Castillia, T. Pertel, S. Olivari, M. G. Grutter, J. Luban
in J Virol (2009) vol. 83 pp3365-73

MicroRNA-221-222 regulate the cell cycle in mast cells
R. J. Mayoral, M. E. Pipkin, M. Pachkov, E. van Nimwegen, A. Rao, S. Monticelli
in J Immunol (2009) vol. 182 pp433-45

Dendritic cell migration to peripheral lymph nodes
A. Martin-Fontecha, A. Lanzavecchia, F. Sallusto
in Handb Exp Pharmacol (2009) pp31-49

Transient depletion of RUNX1/RUNX1T1 by RNA interference delays tumour formation in vivo
N. Martinez Soria, R. Tussiwand, P. Ziegler, M. G. Manz, O. Heidenreich
in Leukemia (2009) vol. 23 pp188-90

2008

The endoplasmic reticulum crossroads for newly synthesized polypeptide chains
T. Cali, O. Vanoni, M. Molinari
in Prog Mol Biol Transl Sci (2008) vol. 83 pp135-79

Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint
A. Manzo, B. Vitolo, F. Humby, R. Caporali, D. Jarrossay, F. Dell'accio, L. Ciardelli, M. Uguccioni, C. Montecucco, C. Pitzalis
in Arthritis Rheum (2008) vol. 58 pp3377-87

CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection
M. Cocco, C. Bellan, R. Tussiwand, D. Corti, E. Traggiai, S. Lazzi, S. Mannucci, L. Bronz, N. Palummo, C. Ginanneschi, P. Tosi, A. Lanzavecchia, M. G. Manz, L. Leoncini
in Am J Pathol (2008) vol. 173 pp1369-78

CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming
A. Martin-Fontecha, D. Baumjohann, G. Guarda, A. Reboldi, M. Hons, A. Lanzavecchia, F. Sallusto
in J Exp Med (2008) vol. 205 pp2561-74

Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels
U. Schenk, A. M. Westendorf, E. Radaelli, A. Casati, M. Ferro, M. Fumagalli, C. Verderio, J. Buer, E. Scanziani, F. Grassi
in Sci Signal (2008) vol. 1 ppra6

Identification of CXCL13 as a new marker for follicular dendritic cell sarcoma
W. Vermi, S. Lonardi, D. Bosisio, M. Uguccioni, G. Danelon, S. Pileri, C. Fletcher, S. Sozzani, F. Zorzi, G. Arrigoni, C. Doglioni, M. Ponzoni, F. Facchetti
in J Pathol (2008) vol. 216 pp356-64

Phenotype and function of human T lymphocyte subsets: consensus and issues
V. Appay, R. A. van Lier, F. Sallusto, M. Roederer
in Cytometry A (2008) vol. 73 pp975-83

Chemokines and leukocyte traffic
F. Sallusto, M. Baggiolini
in Nat Immunol (2008) vol. 9 pp949-52

How chemokines invite leukocytes to dance
M. Thelen, J. V. Stein
in Nat Immunol (2008) vol. 9 pp953-9

A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
T. N. Hartmann, V. Grabovsky, R. Pasvolsky, Z. Shulman, E. C. Buss, A. Spiegel, A. Nagler, T. Lapidot, M. Thelen, R. Alon
in J Leukoc Biol (2008) vol. 84 pp1130-40

Consequences of individual N-glycan deletions and of proteasomal inhibition on secretion of active BACE
O. Vanoni, P. Paganetti, M. Molinari
in Mol Biol Cell (2008) vol. 19 pp4086-98

Intrasplenic trafficking of natural killer cells is redirected by chemokines upon inflammation
C. Gregoire, C. Cognet, L. Chasson, C. A. Coupet, M. Dalod, A. Reboldi, J. Marvel, F. Sallusto, E. Vivier, T. Walzer
in Eur J Immunol (2008) vol. 38 pp2076-84

CXCR7, CXCR4 and CXCL12: an eccentric trio?
M. Thelen, S. Thelen
in J Neuroimmunol (2008) vol. 198 pp9-13

Human T cell development and HIV infection in human hemato-lymphoid system mice
S. Baenziger, P. Ziegler, L. Mazzucchelli, L. Bronz, R. F. Speck, M. G. Manz
in Curr Top Microbiol Immunol (2008) vol. 324 pp125-31

Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities
T. Cali, C. Galli, S. Olivari, M. Molinari
in Biochem Biophys Res Commun (2008) vol. 371 pp405-10

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal
R. Bernasconi, T. Pertel, J. Luban, M. Molinari
in J Biol Chem (2008) vol. 283 pp16446-54

The STATs on dendritic cell development
N. Onai, M. G. Manz
in Immunity (2008) vol. 28 pp490-2

Recombinase-deficient T cell development by selective accumulation of CD3 into lipid rafts
D. Ferrera, M. Panigada, S. Porcellini, F. Grassi
in Eur J Immunol (2008) vol. 38 pp1148-56

Genomics and the immune system
M. E. Pipkin, S. Monticelli
in Immunology (2008) vol. 124 pp23-32

A role for microRNAs in the development of the immune system and in the pathogenesis of cancer
C. Kanellopoulou, S. Monticelli
in Semin Cancer Biol (2008) vol. 18 pp79-88

Of Omenn and mice
V. Marrella, P. L. Poliani, C. Sobacchi, F. Grassi, A. Villa
in Trends Immunol (2008) vol. 29 pp133-40

Cdk9/Cyclin T1 complex: a key player during the activation/differentiation process of normal lymphoid B cells
G. De Falco, E. Leucci, A. Onnis, C. Bellan, C. Tigli, S. Wirths, G. Cerino, M. Cocco, D. Crupi, A. De Luca, A. Lanzavecchia, P. Tosi, L. Leoncini, A. Giordano
in J Cell Physiol (2008) vol. 215 pp276-82

Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge
B. Rockx, D. Corti, E. Donaldson, T. Sheahan, K. Stadler, A. Lanzavecchia, R. Baric
in J Virol (2008) vol. 82 pp3220-35

The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells
L. Lozza, L. Rivino, G. Guarda, D. Jarrossay, A. Rinaldi, F. Bertoni, F. Sallusto, A. Lanzavecchia, J. Geginat
in Eur J Immunol (2008) vol. 38 pp30-9

ER-Associated Folding and Degradation: Learning From Yeast?
R. Bernasconi, M. Molinari
C.B. O’Doherty, A.C. Byrne, Editors
in Protein misfolding (2008) pp113-123

2007

Human monoclonal antibodies by immortalization of memory B cells
A. Lanzavecchia, D. Corti, F. Sallusto
in Curr Opin Biotechnol (2007) vol. 18 pp523-8

Macrophage tolerance: CD47-SIRP-alpha-mediated signals matter
H. Takizawa, M. G. Manz
in Nat Immunol (2007) vol. 8 pp1287-9

Pillars article: Antigen-specific interaction between T and B cells. 1985
A. Lanzavecchia
in J Immunol (2007) vol. 179 pp7206-8

CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesis
A. Manzo, S. Bugatti, R. Caporali, R. Prevo, D. G. Jackson, M. Uguccioni, C. D. Buckley, C. Montecucco, C. Pitzalis
in Am J Pathol (2007) vol. 171 pp1549-62

In and out of the ER: protein folding, quality control, degradation, and related human diseases
D. N. Hebert, M. Molinari
in Physiol Rev (2007) vol. 87 pp1377-408

Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow
N. Onai, A. Obata-Onai, M. A. Schmid, T. Ohteki, D. Jarrossay, M. G. Manz
in Nat Immunol (2007) vol. 8 pp1207-16

Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase
M. A. Barber, S. Donald, S. Thelen, K. E. Anderson, M. Thelen, H. C. Welch
in J Biol Chem (2007) vol. 282 pp29967-76

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
E. V. Acosta-Rodriguez, G. Napolitani, A. Lanzavecchia, F. Sallusto
in Nat Immunol (2007) vol. 8 pp942-9

Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate
S. L. Reiner, F. Sallusto, A. Lanzavecchia
in Science (2007) vol. 317 pp622-5

Substrate-specific requirements for UGT1-dependent release from calnexin
T. Solda, C. Galli, R. J. Kaufman, M. Molinari
in Mol Cell (2007) vol. 27 pp238-49

Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies
Z. Zhu, S. Chakraborti, Y. He, A. Roberts, T. Sheahan, X. Xiao, L. E. Hensley, P. Prabakaran, B. Rockx, I. A. Sidorov, D. Corti, L. Vogel, Y. Feng, J. O. Kim, L. F. Wang, R. Baric, A. Lanzavecchia, K. M. Curtis, G. J. Nabel, K. Subbarao, S. Jiang, D. S. Dimitrov
in Proc Natl Acad Sci U S A (2007) vol. 104 pp12123-8

The central nervous system in mucosal vaccination of rhesus macaques with simian immunodeficiency virus Deltanef
G. Georgsson, C. Stahl-Hennig, K. Tenner-Racz, K. Uberla, H. Stoiber, M. Uguccioni, M. Dierich, R. Ignatius, R. M. Steinman, P. Racz
in Neuropathol Appl Neurobiol (2007) vol. 33 pp644-57

Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza
C. P. Simmons, N. L. Bernasconi, A. L. Suguitan, K. Mills, J. M. Ward, N. V. Chau, T. T. Hien, F. Sallusto, Q. Ha do, J. Farrar, M. D. de Jong, A. Lanzavecchia, K. Subbarao
in PLoS Med (2007) vol. 4 ppe178

L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells
G. Guarda, M. Hons, S. F. Soriano, A. Y. Huang, R. Polley, A. Martin-Fontecha, J. V. Stein, R. N. Germain, A. Lanzavecchia, F. Sallusto
in Nat Immunol (2007) vol. 8 pp743-52

Human-hemato-lymphoid-system mice: opportunities and challenges
M. G. Manz
in Immunity (2007) vol. 26 pp537-41

N-glycan structure dictates extension of protein folding or onset of disposal
M. Molinari
in Nat Chem Biol (2007) vol. 3 pp313-20

Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins
S. Olivari, M. Molinari
in FEBS Lett (2007) vol. 581 pp3658-64

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
E. V. Acosta-Rodriguez, L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, A. Lanzavecchia, F. Sallusto, G. Napolitani
in Nat Immunol (2007) vol. 8 pp639-46

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome
V. Marrella, P. L. Poliani, A. Casati, F. Rucci, L. Frascoli, M. L. Gougeon, B. Lemercier, M. Bosticardo, M. Ravanini, M. Battaglia, M. G. Roncarolo, M. Cavazzana-Calvo, F. Facchetti, L. D. Notarangelo, P. Vezzoni, F. Grassi, A. Villa
in J Clin Invest (2007) vol. 117 pp1260-9

Toll-like receptors and innate immunity in B-cell activation and antibody responses
A. Lanzavecchia, F. Sallusto
in Curr Opin Immunol (2007) vol. 19 pp268-74

Duration, combination and timing: the signal integration model of dendritic cell activation
A. Macagno, G. Napolitani, A. Lanzavecchia, F. Sallusto
in Trends Immunol (2007) vol. 28 pp227-33

Bcl10 controls TCR- and FcgammaR-induced actin polymerization
D. Rueda, O. Gaide, L. Ho, E. Lewkowicz, F. Niedergang, S. Hailfinger, F. Rebeaud, M. Guzzardi, B. Conne, M. Thelen, J. Delon, U. Ferch, T. W. Mak, J. Ruland, J. Schwaller, M. Thome
in J Immunol (2007) vol. 178 pp4373-84

Flt3 in regulation of type I interferon-producing cell and dendritic cell development
N. Onai, A. Obata-Onai, M. A. Schmid, M. G. Manz
in Ann N Y Acad Sci (2007) vol. 1106 pp253-61

The Retroviral Restriction Factor TRIM5alpha
S. Sebastian, J. Luban
in Curr Infect Dis Rep (2007) vol. 9 pp167-73

Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
L. Barfod, N. L. Bernasconi, M. Dahlback, D. Jarrossay, P. H. Andersen, A. Salanti, M. F. Ofori, L. Turner, M. Resende, M. A. Nielsen, T. G. Theander, F. Sallusto, A. Lanzavecchia, L. Hviid
in Mol Microbiol (2007) vol. 63 pp335-47

A single vaccination with attenuated SIVmac 239 via the tonsillar route confers partial protection against challenge with SIVmac 251 at a distant mucosal site, the rectum
C. Stahl-Hennig, M. Eisenblatter, M. Franz, H. Stoiber, K. Tenner-Racz, Y. S. Suh, E. Jasny, B. Falkensammer, M. Uguccioni, G. Georgsson, C. Baroni, M. P. Dierich, J. D. Lifson, R. M. Steinman, K. Uberla, P. Racz, R. Ignatius
in Front Biosci (2007) vol. 12 pp2107-23

Distinct expression pattern of IFN-alpha and TNF-alpha in juvenile idiopathic arthritis synovial tissue
M. Gattorno, L. Chicha, A. Gregorio, F. Ferlito, F. Rossi, D. Jarrossay, A. Lanzavecchia, A. Martini, M. G. Manz
in Rheumatology (Oxford) (2007) vol. 46 pp657-65

Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection
J. Luban
in J Virol (2007) vol. 81 pp1054-61

2006

N-glycan processing in ER quality control
L. W. Ruddock, M. Molinari
in J Cell Sci (2006) vol. 119 pp4373-80

Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases
R. Ghittoni, G. Napolitani, D. Benati, C. Ulivieri, L. Patrussi, F. Laghi Pasini, A. Lanzavecchia, C. T. Baldari
in Eur J Immunol (2006) vol. 36 pp2885-93

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice
S. Baenziger, R. Tussiwand, E. Schlaepfer, L. Mazzucchelli, M. Heikenwalder, M. O. Kurrer, S. Behnke, J. Frey, A. Oxenius, H. Joller, A. Aguzzi, M. G. Manz, R. F. Speck
in Proc Natl Acad Sci U S A (2006) vol. 103 pp15951-6

Microbiology: death of a chaperone
C. Montecucco, M. Molinari
in Nature (2006) vol. 443 pp511-2

EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation
S. Olivari, T. Cali, K. E. Salo, P. Paganetti, L. W. Ruddock, M. Molinari
in Biochem Biophys Res Commun (2006) vol. 349 pp1278-84

N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control
K. W. Moremen, M. Molinari
in Curr Opin Struct Biol (2006) vol. 16 pp592-9

A new role for CCR5 in innate immunity--binding to bacterial heat shock protein 70
C. R. Mackay, F. Sallusto
in Eur J Immunol (2006) vol. 36 pp2293-5

Understanding and making use of human memory B cells
A. Lanzavecchia, N. Bernasconi, E. Traggiai, C. R. Ruprecht, D. Corti, F. Sallusto
in Immunol Rev (2006) vol. 211 pp303-9

Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression
A. U. Rasheed, H. P. Rahn, F. Sallusto, M. Lipp, G. Muller
in Eur J Immunol (2006) vol. 36 pp1892-903

A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression
A. Macagno, M. Molteni, A. Rinaldi, F. Bertoni, A. Lanzavecchia, C. Rossetti, F. Sallusto
in J Exp Med (2006) vol. 203 pp1481-92

Differences in CXCR4-mediated signaling in B cells
E. Palmesino, B. Moepps, P. Gierschik, M. Thelen
in Immunobiology (2006) vol. 211 pp377-89

Toll-like receptor stimulation as a third signal required for activation of human naive B cells
C. R. Ruprecht, A. Lanzavecchia
in Eur J Immunol (2006) vol. 36 pp810-6

Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling
A. F. Campese, A. I. Garbe, F. Zhang, F. Grassi, I. Screpanti, H. von Boehmer
in Blood (2006) vol. 108 pp305-10

Regulation of peripheral T cell activation by calreticulin
S. Porcellini, E. Traggiai, U. Schenk, D. Ferrera, M. Matteoli, A. Lanzavecchia, M. Michalak, F. Grassi
in J Exp Med (2006) vol. 203 pp461-71

A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity
D. Bosisio, I. Marazzi, A. Agresti, N. Shimizu, M. E. Bianchi, G. Natoli
in EMBO J (2006) vol. 25 pp798-810

Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells
S. Infantino, B. Moepps, M. Thelen
in J Immunol (2006) vol. 176 pp2197-207

Plastic downregulation of the transcriptional repressor BCL6 during maturation of human dendritic cells
S. Pantano, D. Jarrossay, S. Saccani, D. Bosisio, G. Natoli
in Exp Cell Res (2006) vol. 312 pp1312-22

Characterization of severe acute respiratory syndrome coronavirus membrane protein
D. Voss, A. Kern, E. Traggiai, M. Eickmann, K. Stadler, A. Lanzavecchia, S. Becker
in FEBS Lett (2006) vol. 580 pp968-73

Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development
N. Onai, A. Obata-Onai, R. Tussiwand, A. Lanzavecchia, M. G. Manz
in J Exp Med (2006) vol. 203 pp227-38

Consequences of ERp57 deletion on oxidative folding of obligate and facultative clients of the calnexin cycle
T. Solda, N. Garbi, G. J. Hammerling, M. Molinari
in J Biol Chem (2006) vol. 281 pp6219-26

2005

The secretory capacity of a cell depends on the efficiency of endoplasmic reticulum-associated degradation
M. Molinari, R. Sitia
in Curr Top Microbiol Immunol (2005) vol. 300 pp1-15

Identification of T cell-restricted genes, and signatures for different T cell responses, using a comprehensive collection of microarray datasets
T. Chtanova, R. Newton, S. M. Liu, L. Weininger, T. R. Young, D. G. Silva, F. Bertoni, A. Rinaldi, S. Chappaz, F. Sallusto, M. S. Rolph, C. R. Mackay
in J Immunol (2005) vol. 175 pp7837-47

Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors
D. Penkov, P. Di Rosa, L. Fernandez Diaz, V. Basso, E. Ferretti, F. Grassi, A. Mondino, F. Blasi
in Mol Cell Biol (2005) vol. 25 pp10768-81

Persistent glycoprotein misfolding activates the glucosidase II/UGT1-driven calnexin cycle to delay aggregation and loss of folding competence
M. Molinari, C. Galli, O. Vanoni, S. M. Arnold, R. J. Kaufman
in Mol Cell (2005) vol. 20 pp503-12

Humanized mice: are we there yet?
F. Macchiarini, M. G. Manz, A. K. Palucka, L. D. Shultz
in J Exp Med (2005) vol. 202 pp1307-11

ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cells
S. Wirths, A. Lanzavecchia
in Eur J Immunol (2005) vol. 35 pp3433-41

P-Rex1 regulates neutrophil function
H. C. Welch, A. M. Condliffe, L. J. Milne, G. J. Ferguson, K. Hill, L. M. Webb, K. Okkenhaug, W. J. Coadwell, S. R. Andrews, M. Thelen, G. E. Jones, P. T. Hawkins, L. R. Stephens
in Curr Biol (2005) vol. 15 pp1867-73

Inhibition of natural type I IFN-producing and dendritic cell development by a small molecule receptor tyrosine kinase inhibitor with Flt3 affinity
R. Tussiwand, N. Onai, L. Mazzucchelli, M. G. Manz
in J Immunol (2005) vol. 175 pp3674-80

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
K. Balabanian, B. Lagane, S. Infantino, K. Y. Chow, J. Harriague, B. Moepps, F. Arenzana-Seisdedos, M. Thelen, F. Bachelerie
in J Biol Chem (2005) vol. 280 pp35760-6

CD molecules 2005: human cell differentiation molecules
H. Zola, B. Swart, I. Nicholson, B. Aasted, A. Bensussan, L. Boumsell, C. Buckley, G. Clark, K. Drbal, P. Engel, D. Hart, V. Horejsi, C. Isacke, P. Macardle, F. Malavasi, D. Mason, D. Olive, A. Saalmueller, S. F. Schlossman, R. Schwartz-Albiez, P. Simmons, T. F. Tedder, M. Uguccioni, H. Warren
in Blood (2005) vol. 106 pp3123-6

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
G. Napolitani, A. Rinaldi, F. Bertoni, F. Sallusto, A. Lanzavecchia
in Nat Immunol (2005) vol. 6 pp769-76

Expression of lymphocyte activation gene 3 (LAG-3) on B cells is induced by T cells
M. Kisielow, J. Kisielow, G. Capoferri-Sollami, K. Karjalainen
in Eur J Immunol (2005) vol. 35 pp2081-8

Human adaptive immune system Rag2-/-gamma(c)-/- mice
L. Chicha, R. Tussiwand, E. Traggiai, L. Mazzucchelli, L. Bronz, J. C. Piffaretti, A. Lanzavecchia, M. G. Manz
in Ann N Y Acad Sci (2005) vol. 1044 pp236-43

The use of calnexin and calreticulin by cellular and viral glycoproteins
M. Pieren, C. Galli, A. Denzel, M. Molinari
in J Biol Chem (2005) vol. 280 pp28265-71

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
C. R. Ruprecht, M. Gattorno, F. Ferlito, A. Gregorio, A. Martini, A. Lanzavecchia, F. Sallusto
in J Exp Med (2005) vol. 201 pp1793-803

The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags
D. N. Hebert, S. C. Garman, M. Molinari
in Trends Cell Biol (2005) vol. 15 pp364-70

Understanding the generation and function of memory T cell subsets
A. Lanzavecchia, F. Sallusto
in Curr Opin Immunol (2005) vol. 17 pp326-32

Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time
G. Natoli, S. Saccani, D. Bosisio, I. Marazzi
in Nat Immunol (2005) vol. 6 pp439-45

Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis
A. Manzo, S. Paoletti, M. Carulli, M. C. Blades, F. Barone, G. Yanni, O. Fitzgerald, B. Bresnihan, R. Caporali, C. Montecucco, M. Uguccioni, C. Pitzalis
in Eur J Immunol (2005) vol. 35 pp1347-59

T cell costimulation by chemokine receptors
B. Molon, G. Gri, M. Bettella, C. Gomez-Mouton, A. Lanzavecchia, A. C. Martinez, S. Manes, A. Viola
in Nat Immunol (2005) vol. 6 pp465-71

Dendritic cells as a tool for the predictive identification of skin sensitisation hazard
S. Casati, P. Aeby, D. A. Basketter, A. Cavani, A. Gennari, G. F. Gerberick, P. Griem, T. Hartung, I. Kimber, J. P. Lepoittevin, B. J. Meade, M. Pallardy, N. Rougier, F. Rousset, G. Rubinstenn, F. Sallusto, G. R. Verheyen, V. Zuang
in Altern Lab Anim (2005) vol. 33 pp47-62

Immune subversion by Helicobacter pylori
C. T. Baldari, A. Lanzavecchia, J. L. Telford
in Trends Immunol (2005) vol. 26 pp199-207

beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide
P. Paganetti, V. Calanca, C. Galli, M. Stefani, M. Molinari
in J Cell Biol (2005) vol. 168 pp863-8

Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway
Q. Gong, D. R. Keeney, M. Molinari, Z. Zhou
in J Biol Chem (2005) vol. 280 pp19419-25

CCL22-induced responses are powerfully enhanced by synergy inducing chemokines via CCR4: evidence for the involvement of first beta-strand of chemokine
S. Sebastiani, G. Danelon, B. Gerber, M. Uguccioni
in Eur J Immunol (2005) vol. 35 pp746-56

Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors
H. Karsunky, M. Merad, I. Mende, M. G. Manz, E. G. Engleman, I. L. Weissman
in Exp Hematol (2005) vol. 33 pp173-81

Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses
Z. Y. Yang, H. C. Werner, W. P. Kong, K. Leung, E. Traggiai, A. Lanzavecchia, G. J. Nabel
in Proc Natl Acad Sci U S A (2005) vol. 102 pp797-801

Analyzing folding and degradation of metabolically labelled polypeptides by conventional and diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis
T. Solda, S. Olivari, M. Molinari
in Biol Proced Online (2005) vol. 7 pp136-43

Sliding doors in the immune response
F. Sallusto, S. L. Reiner
in Nat Immunol (2005) vol. 6 pp10-2

A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation
S. Olivari, C. Galli, H. Alanen, L. Ruddock, M. Molinari
in J Biol Chem (2005) vol. 280 pp2424-8

A rich chemokine environment strongly enhances leukocyte migration and activities
S. Paoletti, V. Petkovic, S. Sebastiani, M. G. Danelon, M. Uguccioni, B. O. Gerber
in Blood (2005) vol. 105 pp3405-12

Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice
S. Feau, V. Facchinetti, F. Granucci, S. Citterio, D. Jarrossay, S. Seresini, M. P. Protti, A. Lanzavecchia, P. Ricciardi-Castagnoli
in Blood (2005) vol. 105 pp697-702

2004

Clonal type I interferon-producing and dendritic cell precursors are contained in both human lymphoid and myeloid progenitor populations
L. Chicha, D. Jarrossay, M. G. Manz
in J Exp Med (2004) vol. 200 pp1519-24

Lead and follow: the dance of the dendritic cell and T cell
A. Lanzavecchia, F. Sallusto
in Nat Immunol (2004) vol. 5 pp1201-2

Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming
A. Martin-Fontecha, L. L. Thomsen, S. Brett, C. Gerard, M. Lipp, A. Lanzavecchia, F. Sallusto
in Nat Immunol (2004) vol. 5 pp1260-5

Chemoattractants and their receptors in homeostasis and inflammation
F. Sallusto, C. R. Mackay
in Curr Opin Immunol (2004) vol. 16 pp724-31

Prostaglandin E2 modulates the functional responsiveness of human monocytes to chemokines
U. Panzer, M. Uguccioni
in Eur J Immunol (2004) vol. 34 pp3682-9

Chemokine receptor expression identifies Pre-T helper (Th)1, Pre-Th2, and nonpolarized cells among human CD4+ central memory T cells
L. Rivino, M. Messi, D. Jarrossay, A. Lanzavecchia, F. Sallusto, J. Geginat
in J Exp Med (2004) vol. 200 pp725-35

Little things that count in transcriptional regulation
G. Natoli
in Cell (2004) vol. 118 pp406-8

EDEM contributes to maintenance of protein folding efficiency and secretory capacity
K. K. Eriksson, R. Vago, V. Calanca, C. Galli, P. Paganetti, M. Molinari
in J Biol Chem (2004) vol. 279 pp44600-5

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus
E. Traggiai, S. Becker, K. Subbarao, L. Kolesnikova, Y. Uematsu, M. R. Gismondo, B. R. Murphy, R. Rappuoli, A. Lanzavecchia
in Nat Med (2004) vol. 10 pp871-5

Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response
S. Saccani, I. Marazzi, A. A. Beg, G. Natoli
in J Exp Med (2004) vol. 200 pp107-13

I-TAC/CXCL11 is a natural antagonist for CCR5
V. Petkovic, C. Moghini, S. Paoletti, M. Uguccioni, B. Gerber
in J Leukoc Biol (2004) vol. 76 pp701-8

Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway
P. Ogilvie, S. Thelen, B. Moepps, P. Gierschik, A. C. da Silva Campos, M. Baggiolini, M. Thelen
in J Immunol (2004) vol. 172 pp6715-22

Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease
M. Merad, P. Hoffmann, E. Ranheim, S. Slaymaker, M. G. Manz, S. A. Lira, I. Charo, D. N. Cook, I. L. Weissman, S. Strober, E. G. Engleman
in Nat Med (2004) vol. 10 pp510-7

Development of a human adaptive immune system in cord blood cell-transplanted mice
E. Traggiai, L. Chicha, L. Mazzucchelli, L. Bronz, J. C. Piffaretti, A. Lanzavecchia, M. G. Manz
in Science (2004) vol. 304 pp104-7

Eotaxin-3/CCL26 is a natural antagonist for CC chemokine receptors 1 and 5. A human chemokine with a regulatory role
V. Petkovic, C. Moghini, S. Paoletti, M. Uguccioni, B. Gerber
in J Biol Chem (2004) vol. 279 pp23357-63

Central memory and effector memory T cell subsets: function, generation, and maintenance
F. Sallusto, J. Geginat, A. Lanzavecchia
in Annu Rev Immunol (2004) vol. 22 pp745-63

Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control
M. Molinari, K. K. Eriksson, V. Calanca, C. Galli, P. Cresswell, M. Michalak, A. Helenius
in Mol Cell (2004) vol. 13 pp125-35

A role for chemokines in the induction of chondrocyte phenotype modulation
I. Mazzetti, G. Magagnoli, S. Paoletti, M. Uguccioni, E. Olivotto, R. Vitellozzi, L. Cattini, A. Facchini, R. M. Borzi
in Arthritis Rheum (2004) vol. 50 pp112-22

Secondary lymphoid tissue chemokine (CCL21) is upregulated in allergic contact dermatitis
H. M. Serra, Y. Eberhard, A. P. Martin, N. Gallino, J. Gagliardi, C. E. Baena-Cagnani, A. R. Lascano, S. Ortiz, A. L. Mariani, M. Uguccioni
in Int Arch Allergy Immunol (2004) vol. 133 pp64-71

CXC and CC chemokine expression in inflamed and noninflamed pelvic ileal pouch tissue
U. Helwig, P. Gionchetti, F. Rizzello, K. Lammers, T. Kuhbacher, S. Schreiber, M. Baggiolini, M. Uguccioni, M. Campieri
in Int J Colorectal Dis (2004) vol. 19 pp165-70

Bridging the bone marrow–thymus gap
MG Manz
in Blood (2004) vol. 103 pp2869

Endoplasmic Reticulum-Associated Protein Degradation
M. Molinari
W.J. Lennarz, M.D. Lane, Editors
in Encyclopedia of Biological Chemistry (2004) vol. 2 pp20-23

The Protein Factory
M. Molinari
in Protocols of the 30th Seminars of Biological Evolution (2004) vol. 108 pp117-122

2003

Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation
G. Napolitani, N. Bortoletto, L. Racioppi, A. Lanzavecchia, U. D'Oro
in Eur J Immunol (2003) vol. 33 pp2832-41

Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
A. Martin-Fontecha, S. Sebastiani, U. E. Hopken, M. Uguccioni, M. Lipp, A. Lanzavecchia, F. Sallusto
in J Exp Med (2003) vol. 198 pp615-21

Expression of CS-1 fibronectin precedes monocyte chemoattractant protein-1 production during elicitation of allergic contact dermatitis
A. P. Martin, J. Gagliardi, C. E. Baena-Cagnani, Y. Eberhard, M. Uguccioni, N. Gallino, A. L. Mariani, H. M. Serra
in Clin Exp Allergy (2003) vol. 33 pp1118-24

Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo
H. Karsunky, M. Merad, A. Cozzio, I. L. Weissman, M. G. Manz
in J Exp Med (2003) vol. 198 pp305-13

Modulation of NF-kappaB activity by exchange of dimers
S. Saccani, S. Pantano, G. Natoli
in Mol Cell (2003) vol. 11 pp1563-74

Cytokine-driven proliferation and differentiation of human naive, central memory and effector memory CD4+ T cells
J. Geginat, F. Sallusto, A. Lanzavecchia
in Pathol Biol (Paris) (2003) vol. 51 pp64-6

Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors
D. Hanahan, A. Lanzavecchia, E. Mihich
in Cancer Res (2003) vol. 63 pp3005-8

Antigen dependent and independent mechanisms that sustain serum antibody levels
E. Traggiai, R. Puzone, A. Lanzavecchia
in Vaccine (2003) vol. 21 Suppl 2 ppS35-7

Mitotic and stress-induced phosphorylation of HsPI3K-C2alpha targets the protein for degradation
S. A. Didichenko, C. M. Fragoso, M. Thelen
in J Biol Chem (2003) vol. 278 pp26055-64

Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes
P. Ogilvie, S. Paoletti, I. Clark-Lewis, M. Uguccioni
in Blood (2003) vol. 102 pp789-94

Kinetics and expression patterns of chemokine receptors in human CD4+ T lymphocytes primed by myeloid or plasmacytoid dendritic cells
A. Langenkamp, K. Nagata, K. Murphy, L. Wu, A. Lanzavecchia, F. Sallusto
in Eur J Immunol (2003) vol. 33 pp474-82

T cell fitness determined by signal strength
A. V. Gett, F. Sallusto, A. Lanzavecchia, J. Geginat
in Nat Immunol (2003) vol. 4 pp355-60

Biology of hematopoietic stem cells and progenitors: implications for clinical application
M. Kondo, A. J. Wagers, M. G. Manz, S. S. Prohaska, D. C. Scherer, G. F. Beilhack, J. A. Shizuru, I. L. Weissman
in Annu Rev Immunol (2003) vol. 21 pp759-806

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle
M. Molinari, V. Calanca, C. Galli, P. Lucca, P. Paganetti
in Science (2003) vol. 299 pp1397-400

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines
J. Geginat, A. Lanzavecchia, F. Sallusto
in Blood (2003) vol. 101 pp4260-6

A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
N. L. Bernasconi, N. Onai, A. Lanzavecchia
in Blood (2003) vol. 101 pp4500-4

Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes
M. Messi, I. Giacchetto, K. Nagata, A. Lanzavecchia, G. Natoli, F. Sallusto
in Nat Immunol (2003) vol. 4 pp78-86

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma
J. R. Smith, R. M. Braziel, S. Paoletti, M. Lipp, M. Uguccioni, J. T. Rosenbaum
in Blood (2003) vol. 101 pp815-21

2002

Growth-related oncogene alpha induction of apoptosis in osteoarthritis chondrocytes
R. M. Borzi, I. Mazzetti, G. Magagnoli, S. Paoletti, M. Uguccioni, R. Gatti, G. Orlandini, L. Cattini, A. Facchini
in Arthritis Rheum (2002) vol. 46 pp3201-11

Maintenance of serological memory by polyclonal activation of human memory B cells
N. L. Bernasconi, E. Traggiai, A. Lanzavecchia
in Science (2002) vol. 298 pp2199-202

A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding
J. Rachmilewitz, A. Lanzavecchia
in Trends Immunol (2002) vol. 23 pp592-5

Progressive differentiation and selection of the fittest in the immune response
A. Lanzavecchia, F. Sallusto
in Nat Rev Immunol (2002) vol. 2 pp982-7

TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines
J. Geginat, S. Campagnaro, F. Sallusto, A. Lanzavecchia
in Adv Exp Med Biol (2002) vol. 512 pp107-12

Optimizing anti-CD3 affinity for effective T cell targeting against tumor cells
N. Bortoletto, E. Scotet, Y. Myamoto, U. D'Oro, A. Lanzavecchia
in Eur J Immunol (2002) vol. 32 pp3102-7

Early postnatal death and motor disorders in mice congenitally deficient in calnexin expression
A. Denzel, M. Molinari, C. Trigueros, J. E. Martin, S. Velmurgan, S. Brown, G. Stamp, M. J. Owen
in Mol Cell Biol (2002) vol. 22 pp7398-404

Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes
S. Saccani, G. Natoli
in Genes Dev (2002) vol. 16 pp2219-24

Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER
M. Molinari, C. Galli, V. Piccaluga, M. Pieren, P. Paganetti
in J Cell Biol (2002) vol. 158 pp247-57

T cell priming by dendritic cells: thresholds for proliferation, differentiation and death and intraclonal functional diversification
A. Langenkamp, G. Casorati, C. Garavaglia, P. Dellabona, A. Lanzavecchia, F. Sallusto
in Eur J Immunol (2002) vol. 32 pp2046-54

The instructive role of dendritic cells on T-cell responses
F. Sallusto, A. Lanzavecchia
in Arthritis Res (2002) vol. 4 Suppl 3 ppS127-32

Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes
H. Yoneyama, S. Narumi, Y. Zhang, M. Murai, M. Baggiolini, A. Lanzavecchia, T. Ichida, H. Asakura, K. Matsushima
in J Exp Med (2002) vol. 195 pp1257-66

CD antigens 2002
D. Mason, P. Andre, A. Bensussan, C. Buckley, C. Civin, E. Clark, M. de Haas, S. Goyert, M. Hadam, D. Hart, V. Horejsi, S. Meuer, J. Morrissey, R. Schwartz-Albiez, S. Shaw, D. Simmons, M. Uguccioni, E. van der Schoot, E. Vivier, H. Zola
in Blood (2002) vol. 99 pp3877-80

Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22
P. Ghia, G. Strola, L. Granziero, M. Geuna, G. Guida, F. Sallusto, N. Ruffing, L. Montagna, P. Piccoli, M. Chilosi, F. Caligaris-Cappio
in Eur J Immunol (2002) vol. 32 pp1403-13

The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity
F. Fischer, M. Molinari, U. Bodendorf, P. Paganetti
in J Neurochem (2002) vol. 80 pp1079-88

Effects of the adjuvant cholera toxin on dendritic cells: stimulatory and inhibitory signals that result in the amplification of immune responses
M. C. Gagliardi, F. Sallusto, M. Marinaro, S. Vendetti, A. Riccomi, M. T. De Magistris
in Int J Med Microbiol (2002) vol. 291 pp571-5

Analyzing cotranslational protein folding and disulfide formation by diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis
M. Molinari, A. Helenius
in Methods Enzymol (2002) vol. 348 pp35-42

Folding of viral glycoproteins in the endoplasmic reticulum
M. Molinari
in Virus Res (2002) vol. 82 pp83-6

Reference: CD Antigens 2002
D. Mason, P. Andre, A. Bensussan, C. Buckley, C. Civin, E. Clark, M. de Haas, S. Goyert, M. Hadam, D. Hart, V. Horejsi, S. Meuer, J. Morrissey, R. Schwartz-Albiez, S. Shaw, D. Simmons, M. Uguccioni, E. van der Schoot, E. Vivier, H. Zola
in J Immunol (2002) vol. 168 pp2083-6

The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells
A. Engering, T. B. Geijtenbeek, S. J. van Vliet, M. Wijers, E. van Liempt, N. Demaurex, A. Lanzavecchia, J. Fransen, C. G. Figdor, V. Piguet, Y. van Kooyk
in J Immunol (2002) vol. 168 pp2118-26

CD Antigens 2001
D. Mason, P. Andre, A. Bensussan, C. Buckley, C. Civin, E. Clark, M. de Haas, S. Goyert, M. Hadam, D. Hart, V. Horejsi, S. Meuer, J. Morrissey, R. Schwartz-Albiez, S. Shaw, D. Simmons, M. Uguccioni, E. van der Schoot, E. Vivier, H. Zola
in Mod Pathol (2002) vol. 15 pp71-6

Lack of fair play in the T cell response
A. Lanzavecchia
in Nat Immunol (2002) vol. 3 pp9-10

p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment
S. Saccani, S. Pantano, G. Natoli
in Nat Immunol (2002) vol. 3 pp69-75

2001

Origin and migratory properties of dendritic cells in the skin
F. Sallusto
in Curr Opin Allergy Clin Immunol (2001) vol. 1 pp441-8

CD antigens 2001
D. Y. Mason, P. Andre, A. Bensussan, C. Buckley, C. Civin, E. Clark, M. de Haas, S. Goyert, M. Hadam, D. Hart, V. Horejsi, S. Meuer, J. Morissey, R. Schwartz-Albiez, S. Shaw, D. Simmons, M. Uguccioni, E. van der Schoot, E. Viver, H. Zola
in Tissue Antigens (2001) vol. 58 pp425-30

BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction
A. Dzionek, Y. Sohma, J. Nagafune, M. Cella, M. Colonna, F. Facchetti, G. Gunther, I. Johnston, A. Lanzavecchia, T. Nagasaka, T. Okada, W. Vermi, G. Winkels, T. Yamamoto, M. Zysk, Y. Yamaguchi, J. Schmitz
in J Exp Med (2001) vol. 194 pp1823-34

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells
J. Geginat, F. Sallusto, A. Lanzavecchia
in J Exp Med (2001) vol. 194 pp1711-9

Mouse pre-immunocytes as non-proliferating multipotent precursors of macrophages, interferon-producing cells, CD8alpha(+) and CD8alpha(-) dendritic cells
L. Bruno, T. Seidl, A. Lanzavecchia
in Eur J Immunol (2001) vol. 31 pp3403-12

Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
D. Jarrossay, G. Napolitani, M. Colonna, F. Sallusto, A. Lanzavecchia
in Eur J Immunol (2001) vol. 31 pp3388-93

CD antigens 2001: aims and results of HLDA Workshops
D. Mason, P. Andre, A. Bensussan, C. Buckley, C. Civin, E. Clark, M. de Haas, S. Goyert, M. Hadam, D. Hart, V. Horejsi, S. Meuer, J. Morrissey, R. Schwartz-Albiez, S. Shaw, D. Simmons, M. Uguccioni, E. van der Schoot, E. Vivier, H. Zola
in Stem Cells (2001) vol. 19 pp556-62

CD antigens 2001
D. Mason, P. Andre, A. Bensussan, C. Buckley, C. Civin, E. Clark, M. de Haas, S. Goyert, M. Hadam, D. Hart, V. Horejsi, S. Meuer, J. Morrissey, R. Schwartz-Albiez, S. Shaw, D. Simmons, M. Uguccioni, E. van der Schoot, E. Vivier, H. Zola
in J Leukoc Biol (2001) vol. 70 pp685-90

Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles
S. A. Didichenko, M. Thelen
in J Biol Chem (2001) vol. 276 pp48135-42

Is dimerization of chemokine receptors functionally relevant?
M. Thelen, M. Baggiolini
in Sci STKE (2001) vol. 2001 ppPE34

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
S. M. Maira, I. Galetic, D. P. Brazil, S. Kaech, E. Ingley, M. Thelen, B. A. Hemmings
in Science (2001) vol. 294 pp374-80

Exploring pathways for memory T cell generation
F. Sallusto, A. Lanzavecchia
in J Clin Invest (2001) vol. 108 pp805-6

Regulation of T cell immunity by dendritic cells
A. Lanzavecchia, F. Sallusto
in Cell (2001) vol. 106 pp263-6

Two waves of nuclear factor kappaB recruitment to target promoters
S. Saccani, S. Pantano, G. Natoli
in J Exp Med (2001) vol. 193 pp1351-9

The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics
A. Lanzavecchia, F. Sallusto
in Curr Opin Immunol (2001) vol. 13 pp291-8

Antigen decoding by T lymphocytes: from synapses to fate determination
A. Lanzavecchia, F. Sallusto
in Nat Immunol (2001) vol. 2 pp487-92

Expression and immunogenicity of oncofetal antigen-immature laminin receptor in human renal cell carcinoma
C. Zelle-Rieser, A. L. Barsoum, F. Sallusto, R. Ramoner, J. W. Rohrer, L. Holtl, G. Bartsch, Jh Jr Coggin, M. Thurnher
in J Urol (2001) vol. 165 pp1705-9

Migration and function of antigen-primed nonpolarized T lymphocytes in vivo
G. Iezzi, D. Scheidegger, A. Lanzavecchia
in J Exp Med (2001) vol. 193 pp987-93

Dancing to the tune of chemokines
M. Thelen
in Nat Immunol (2001) vol. 2 pp129-34

Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5
P. Ogilvie, G. Bardi, I. Clark-Lewis, M. Baggiolini, M. Uguccioni
in Blood (2001) vol. 97 pp1920-4

Kinetics of GATA-3 gene expression in early polarizing and committed human T cells
E. Lantelme, S. Mantovani, B. Palermo, R. Campanelli, F. Sallusto, C. Giachino
in Immunology (2001) vol. 102 pp123-30

Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes
M. B. Delgado, I. Clark-Lewis, P. Loetscher, H. Langen, M. Thelen, M. Baggiolini, M. Wolf
in Eur J Immunol (2001) vol. 31 pp699-707

Organization of plasma membrane functional rafts upon T cell activation
L. Tuosto, I. Parolini, S. Schroder, M. Sargiacomo, A. Lanzavecchia, A. Viola
in Eur J Immunol (2001) vol. 31 pp345-9

Rac and phosphatidylinositol 3-kinase regulate the protein kinase B in Fc epsilon RI signaling in RBL 2H3 mast cells
N. Djouder, G. Schmidt, M. Frings, A. Cavalie, M. Thelen, K. Aktories
in J Immunol (2001) vol. 166 pp1627-34

Antigen processing and recognition
P. Cresswell, A. Lanzavecchia
in Curr Opin Immunol (2001) vol. 13 pp11-2

2000

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells
A. Langenkamp, M. Messi, A. Lanzavecchia, F. Sallusto
in Nat Immunol (2000) vol. 1 pp311-6

Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization
M. Cella, F. Facchetti, A. Lanzavecchia, M. Colonna
in Nat Immunol (2000) vol. 1 pp305-10

Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression
F. Sallusto, A. Lanzavecchia
in Immunol Rev (2000) vol. 177 pp134-40

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
D. Breitfeld, L. Ohl, E. Kremmer, J. Ellwart, F. Sallusto, M. Lipp, R. Forster
in J Exp Med (2000) vol. 192 pp1545-52

Evidence for a pool of coronin in mammalian cells that is sensitive to PI 3-kinase
S. A. Didichenko, A. W. Segal, M. Thelen
in FEBS Lett (2000) vol. 485 pp147-52

A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response
P. R. Dunbar, C. L. Smith, D. Chao, M. Salio, D. Shepherd, F. Mirza, M. Lipp, A. Lanzavecchia, F. Sallusto, A. Evans, R. Russell-Jones, A. L. Harris, V. Cerundolo
in J Immunol (2000) vol. 165 pp6644-52

Functional subsets of memory T cells identified by CCR7 expression
F. Sallusto, A. Langenkamp, J. Geginat, A. Lanzavecchia
in Curr Top Microbiol Immunol (2000) vol. 251 pp167-71

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells
A. Lanzavecchia, F. Sallusto
in Science (2000) vol. 290 pp92-7

Human chondrocytes express functional chemokine receptors and release matrix-degrading enzymes in response to C-X-C and C-C chemokines
R. M. Borzi, I. Mazzetti, L. Cattini, M. Uguccioni, M. Baggiolini, A. Facchini
in Arthritis Rheum (2000) vol. 43 pp1734-41

Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes
B. Tilton, L. Ho, E. Oberlin, P. Loetscher, F. Baleux, I. Clark-Lewis, M. Thelen
in J Exp Med (2000) vol. 192 pp313-24

The role of chemokine receptors in primary, effector, and memory immune responses
F. Sallusto, C. R. Mackay, A. Lanzavecchia
in Annu Rev Immunol (2000) vol. 18 pp593-620

From synapses to immunological memory: the role of sustained T cell stimulation
A. Lanzavecchia, F. Sallusto
in Curr Opin Immunol (2000) vol. 12 pp92-8