David Jarrossay
Immune Regulation
Scientist, Responsible for the flow cytometry Facility
Via Vela, 6
6500 Bellinzona,
Switzerland
- david.jarrossay@irb.usi.ch
- +41 91 820 0331
- +41 91 820 0305
| Bio |
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David Jarrossay studied biology in Clermont-Ferrand (France) where he earned a degree of engineer in biotechnologies in 1991. He then moved to Marseille to work for Immunotech, a biotech company specialized in the production of antibodies where he was in charge of evaluating and developing new clones for the research. In 2000, he moved to Bellinzona where he became responsible for the FACS facility. He started there a research project on the two major subsets of circulating dendritic cells showing their specialization and complementarity. He received in 2005 a PhD degree from the University of Fribourg (CH). He’s now head of the imaging facility of the IRB. He’s also conducting research projects on plasma cells and B cells. |
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Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta C. E. Zielinski, F. Mele, D. Aschenbrenner, D. Jarrossay, F. Ronchi, M. Gattorno, S. Monticelli, A. Lanzavecchia, F. Sallusto in Nature (2012) vol. 484 pp514-8 |
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A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins D. Corti, J. Voss, S. J. Gamblin, G. Codoni, A. Macagno, D. Jarrossay, S. G. Vachieri, D. Pinna, A. Minola, F. Vanzetta, C. Silacci, B. M. Fernandez-Rodriguez, G. Agatic, S. Bianchi, I. Giacchetto-Sasselli, L. Calder, F. Sallusto, P. Collins, L. F. Haire, N. Temperton, J. P. Langedijk, J. J. Skehel, A. Lanzavecchia in Science (2011) vol. 333 pp850-6 |
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CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses N. Chevalier, D. Jarrossay, E. Ho, D. T. Avery, C. S. Ma, D. Yu, F. Sallusto, S. G. Tangye, C. R. Mackay in J Immunol (2011) vol. 186 pp5556-68 |
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CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function L. Rivino, P. Gruarin, B. Haringer, S. Steinfelder, L. Lozza, B. Steckel, A. Weick, E. Sugliano, D. Jarrossay, A. A. Kuhl, C. Loddenkemper, S. Abrignani, F. Sallusto, A. Lanzavecchia, J. Geginat in J Exp Med (2010) vol. 207 pp565-77 |
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Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals D. Corti, J. P. Langedijk, A. Hinz, M. S. Seaman, F. Vanzetta, B. M. Fernandez-Rodriguez, C. Silacci, D. Pinna, D. Jarrossay, S. Balla-Jhagjhoorsingh, B. Willems, M. J. Zekveld, H. Dreja, E. O'Sullivan, C. Pade, C. Orkin, S. A. Jeffs, D. C. Montefiori, D. Davis, W. Weissenhorn, A. McKnight, J. L. Heeney, F. Sallusto, Q. J. Sattentau, R. A. Weiss, A. Lanzavecchia in PLoS One (2010) vol. 5 ppe8805 |
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Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells T. Duhen, R. Geiger, D. Jarrossay, A. Lanzavecchia, F. Sallusto in Nat Immunol (2009) vol. 10 pp857-63 |
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Clonal dissection of the human memory B-cell repertoire following infection and vaccination D. Pinna, D. Corti, D. Jarrossay, F. Sallusto, A. Lanzavecchia in Eur J Immunol (2009) vol. 39 pp1260-70 |
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Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint A. Manzo, B. Vitolo, F. Humby, R. Caporali, D. Jarrossay, F. Dell'accio, L. Ciardelli, M. Uguccioni, C. Montecucco, C. Pitzalis in Arthritis Rheum (2008) vol. 58 pp3377-87 |
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The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells L. Lozza, L. Rivino, G. Guarda, D. Jarrossay, A. Rinaldi, F. Bertoni, F. Sallusto, A. Lanzavecchia, J. Geginat in Eur J Immunol (2008) vol. 38 pp30-9 |
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Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow N. Onai, A. Obata-Onai, M. A. Schmid, T. Ohteki, D. Jarrossay, M. G. Manz in Nat Immunol (2007) vol. 8 pp1207-16 |
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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells E. V. Acosta-Rodriguez, L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, A. Lanzavecchia, F. Sallusto, G. Napolitani in Nat Immunol (2007) vol. 8 pp639-46 |
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Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA L. Barfod, N. L. Bernasconi, M. Dahlback, D. Jarrossay, P. H. Andersen, A. Salanti, M. F. Ofori, L. Turner, M. Resende, M. A. Nielsen, T. G. Theander, F. Sallusto, A. Lanzavecchia, L. Hviid in Mol Microbiol (2007) vol. 63 pp335-47 |
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Distinct expression pattern of IFN-alpha and TNF-alpha in juvenile idiopathic arthritis synovial tissue M. Gattorno, L. Chicha, A. Gregorio, F. Ferlito, F. Rossi, D. Jarrossay, A. Lanzavecchia, A. Martini, M. G. Manz in Rheumatology (Oxford) (2007) vol. 46 pp657-65 |
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Plastic downregulation of the transcriptional repressor BCL6 during maturation of human dendritic cells S. Pantano, D. Jarrossay, S. Saccani, D. Bosisio, G. Natoli in Exp Cell Res (2006) vol. 312 pp1312-22 |
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Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA B. Scheel, R. Teufel, J. Probst, J. P. Carralot, J. Geginat, M. Radsak, D. Jarrossay, H. Wagner, G. Jung, H. G. Rammensee, I. Hoerr, S. Pascolo in Eur J Immunol (2005) vol. 35 pp1557-66 |
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Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice S. Feau, V. Facchinetti, F. Granucci, S. Citterio, D. Jarrossay, S. Seresini, M. P. Protti, A. Lanzavecchia, P. Ricciardi-Castagnoli in Blood (2005) vol. 105 pp697-702 |
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Clonal type I interferon-producing and dendritic cell precursors are contained in both human lymphoid and myeloid progenitor populations L. Chicha, D. Jarrossay, M. G. Manz in J Exp Med (2004) vol. 200 pp1519-24 |
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Chemokine receptor expression identifies Pre-T helper (Th)1, Pre-Th2, and nonpolarized cells among human CD4+ central memory T cells L. Rivino, M. Messi, D. Jarrossay, A. Lanzavecchia, F. Sallusto, J. Geginat in J Exp Med (2004) vol. 200 pp725-35 |
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Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells D. Jarrossay, G. Napolitani, M. Colonna, F. Sallusto, A. Lanzavecchia in Eur J Immunol (2001) vol. 31 pp3388-93 |
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Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment M. Mohty, D. Jarrossay, M. Lafage-Pochitaloff, C. Zandotti, F. Briere, X. N. de Lamballeri, D. Isnardon, D. Sainty, D. Olive, B. Gaugler in Blood (2001) vol. 98 pp3750-6 |
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The monoclonal antibody 97A6 defines a novel surface antigen expressed on human basophils and their multipotent and unipotent progenitors H. J. Buhring, P. J. Simmons, M. Pudney, R. Muller, D. Jarrossay, A. van Agthoven, M. Willheim, W. Brugger, P. Valent, L. Kanz in Blood (1999) vol. 94 pp2343-56 |
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Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon M. Cella, D. Jarrossay, F. Facchetti, O. Alebardi, H. Nakajima, A. Lanzavecchia, M. Colonna in Nat Med (1999) vol. 5 pp919-23 |